Papalymo Totolymo's first ability resolves before the spell that caused it to trigger. It resolves even if that spell is countered or otherwise leaves the stack.

While resolving Papalymo Totolymo's second ability, the next opponent in turn order who lost life this turn chooses a creature with the greatest power among creatures they control, then each other opponent who lost life this turn in turn order does the same. Then each of the chosen creatures are sacrificed simultaneously.